Updated NP Descriptions

CVS Health Clinical Trial Services LLC, a CVS Health company. CVS Health Clinical Trial Services LLC (CVS Health CTS) provides scientific, technical, and management expertise, and related services as they relate to healthcare epidemiology research for governmental agencies, external organizations, and industry. Services include real-world evidence studies and clinical trial services such as recruitment of patients and conducting trials.  CVS Health is a premier health company that provides a range of health services including pharmacy benefit management (PBM), retail and long-term care including Minute Clinic services, Aetna health care benefits, and other services. 

The CVS Health CTS, Safety Surveillance & Collaboration (CTS SS&C) team uses Aetna health care benefits data to actively monitor and evaluate safety in the US population. SS&C uses the Aetna enterprise data warehouse that includes medical and pharmacy health plan membership, medical and pharmacy health plan eligibility, medical claims, outpatient pharmacy claims, and outpatient lab test results, for Aetna’s non-administrative services Commercial members and Medicare Advantage.   The SS&C maintains the Aetna Sentinel Common Data Model (SCDM) which has over 50 million patients available for research purposes with up to 14 years of healthcare experience. CTS SS&C also transforms the Aetna administrative and clinical data into Biologics Effectiveness & Safety (BEST) Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM), and the Aetna Patient-Centered Outcomes Research Institute (PCORI) CDM. 

Harvard Pilgrim Health Care is one of the country's premier health plans. It is a large non-profit health plan with diverse enrollees across New England. Approximately 3.8 million researchable lives (both current and former enrollees) are available for study by Harvard Pilgrim Health Care Institute (HPHCI), a research and academic partnership between Harvard Medical School and Harvard Pilgrim Health Care. HPHCI also participates in the IMEDS program as the IMEDS Analytic Center. 

HealthCore, Inc., a wholly-owned subsidiary of Elevance Health, uses real-world data to conduct outcomes, health economics, pharmacoepidemiologic, and late phase research. The HealthCore Integrated Research Database is a proprietary, fully integrated, longitudinal claims database that combines medical, pharmacy, and laboratory information drawn nearly 80 million unique individuals with medical coverage and nearly 62 million researchable lives with medical and pharmacy claims information since 2006. In addition, The HealthCore Integrated Research Environment has the ability to link the claims data in the HealthCore Integrated Research Database to complementary data sources, including inpatient and outpatient medical records, national vital statistics records, cancer and vaccine registries (state-by-state), disease and device registries, member and provider surveys, and point of care clinical data. Using these resources, HealthCore conducts a range of real world research designed to meet client needs, including retrospective database studies, medical record review studies, cross-sectional and longitudinal patient and provider surveys, and prospective site-based studies, including pragmatic clinical trials.

HealthPartners Institute (the Institute) is a 501c(3) nonprofit organization dedicated to conducting high-quality, public-domain health research, often in collaboration with other academic and research organizations throughout the world. HealthPartners Institute employs 33 career research investigators and more than 400 clinician researchers and encompasses vast and varied areas of research including neurosciences, critical care, dental and oral health, maternal and child health, chronic disease, cancer, clinical research, health economics, mental health, Struthers Parkinson’s Center, and Park Nicollet International Diabetes Center. In addition to our participation in the Innovation in Medical Evidence Development and Surveillance (IMEDS) network, the Institute also participates in several national research networks including the Health Care Systems Research Network, the Vaccine Safety Datalink, the Sentinel Initiative, the Biologics and Biosimilars Collective Intelligence Consortium (BBCIC), and the Mental Health Research Network (MHRN). The Institute is linked to an integrated health care system that provides health insurance for more than 1 million members and health care for more than 1.2 million patients. 

Humana/Humana Healthcare Research is a health economics and outcomes research subsidiary of Humana, which focuses on treatment effectiveness, drug safety, adherence, medical and pharmacy benefit design, disease management programs, and other healthcare services. Humana/Humana Healthcare Research has been an active collaborator and Data Partner in the FDA Sentinel System, the Patient-Centered Outcomes Research Institute's National Patient-Centered Research Network, and several Distributed Research Network initiatives. More than 27 million researchable lives are available for research within this health system since 2007. Humana’s geographic coverage for the IMEDS research population includes every U.S. state and is predominantly a Medicare population. 

Kaiser Permanente Washington Health Research Institute (KPWHRI) has been a Sentinel Partner since its inception and has recently joined the IMEDS Network. KPWHRI is the public-interest research arm of Kaiser Permanente Washington, a nonprofit integrated healthcare organization. Research at KPWHRI is led by a faculty of investigators, collaborative scientists, and biostatisticians; the faculty includes individuals with graduate training and experience in medicine, psychology, epidemiology, biostatistics, economics, anthropology, and other relevant disciplines. Nationally recognized for rigorous and innovative methods, researchers typically work in interdisciplinary teams, bringing new perspectives to challenging questions. Most KPWHRI faculty members have secondary appointments at the University of Washington, Fred Hutchinson Cancer Research Center, or other academic institutions, contributing to teaching and research there. They also help train tomorrow’s scientific leaders, including postdoctoral fellows and UW students. Kaiser Permanente Washington’s population includes 680,000 researchable lives throughout the Pacific Northwest, primarily within Washington State. As an integrated system, KPWA maintains electronic health record and claims data for its entire population, and these data are available for public health research. In 2017, Kaiser Permanente acquired Group Health Cooperative, and the healthcare system then became Kaiser Permanente Washington. Previously, Group Health had been providing care to members in Washington State since 1947, and as a result electronic health data that go back for decades, including pharmacy data dating back to 1977, are available for research use. 

Marshfield Clinic Health System is an integrated system serving mostly rural central, northern, and northwestern Wisconsin with more than 10,000 employees and more than 1,200 providers comprising 86 medical specialties and sub-specialties, a health plan, and longstanding research and education programs. The Clinic has approximately 3.5 million patient encounters each year at more than 50 clinics and 12 hospitals. Data from more than 400,000 unique patients (past and present) since 2000 who are insured by Security Health Plan and seek care in the Marshfield Clinic Health System are available for research. 

Vanderbilt University Medical Center is a comprehensive health care facility dedicated to patient care, research, and the education of health care professionals. Its reputation for excellence in each of these areas has made Vanderbilt a major patient referral center for the South, Southeast and Midwest. The geographic coverage for the population that is included for IMEDS research includes the state of Tennessee through Tennessee Medicaid (TennCare). TennCare insures approximately 1.4 million Tennesseans annually, with an over-representation of women of child-bearing age and children. Fifty percent of women giving birth in Tennessee are insured by TennCare at the time of birth. VUMC has a long history of using these data for pharmacoepidemiologic research, with review and approval by the Division of TennCare. TennCare data is used for Sentinel and IMEDS analyses and includes more than 3.4 4.4 million past and present researchable lives (900,000 current). 

University of Massachusetts Chan Medical School Division of Health Systems Science (UMMS HSS).  UMMS HSS seeks to advance research, education, and practice in how care is delivered to, and experienced by patients.  We are committed to improving population health, reducing costs of care, enhancing patient experience, and promoting provider wellness. UMMS HSS has access to claims data from 261,000 members of Fallon Health (annual member enrollment; approximately 1,032,000 unique patients overall), with the capability to link to electronic health record data for 35% of members who are cared for at Reliant Medical Group practices. The geographic coverage for the population that is included for IMEDS research includes Massachusetts, Connecticut, Rhode Island, and New Hampshire.